Keitaro Koga (M2) gave an organised session at the international conference SICE Annual Conference 2021. Molecular Cybernetics/Robotics & Synthesis/Systems Biology (Thursday 9 September 2021), where he gave an oral presentation.
Programme.
https://controls.papercept.net/conferences/conferences/SICE21/program/SICE21_ContentListWeb_3.html#tha01
SICE Annual Conference 2021 is an international conference organised by the Society of Instrument and Control Engineers. It was originally scheduled to take place in Tokyo, but due to the impact of the spread of the new coronavirus infection, an online format was used.
K. Koga, T. Koga and T. Nakakubo, New approaches to frequency response analysis of biomolecular circuits,
Proceedings of the SICE Annual Conference (SICE2021), Tokyo (online), Sep, 2021.
Abstract: This study proposes a new approach to frequency response analysis of biomolecular circuits. The following biomolecular circuits are considered: enzyme-free DNA reaction systems that utilise DNA strand displacement reactions. As biomolecular circuits are non-linear in nature, it is generally difficult to apply linear control theory without linearisation. In a group of DNA circuits, the DNA strands in a reaction system can be divided into two groups: fuel strands and signal strands. Here, we show that frequency response analysis can be applied by transforming the original non-linear model into a two-time scale model. The novelty of the method is demonstrated using two practical examples.
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